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When administered with a potent inhibitor of CYP3A4, a low dose of buspirone and caution are recommended. 5 mg/kg sulpiride significantly increased punished responding Low-dose buspirone, melatonin and low-dose bupropion added to mood stabilizers for severe treatment-resistant bipolar depression Psychother Psychosom. 4 However, most patients respond to a dose in the range of 15 mg to 30 mg Buspirone is metabolized primarily by CYP3A4. Buspirone Dosage for Anxiety Disorders. The usefulness of this drug should be periodically reassessed if used for extended periods. The maximum daily dosage should not exceed 60 mg per day explore counseling services book a session Buspirone (BuSpar) Dosages Buspirone is available as a 5mg, 7. 5mg, 10mg, 15mg or 30mg tablet for oral consumption. The recommended initial dose is 15 mg daily (7. All listed dosages are according to the drug manufacturer This is a fairly common side effect when initiating Buspar therapy: *Psychiatric. Common (1% to 10%): Insomnia, nervousness, excitement, anger/hostility, confusion, depression, dream disturbances, attention disturbance, sleep disorder*. Low doses of buspirone, as well as subsequent dose adjustments, may be required during coadministration of moderate CYP3A4 inhibitors Low doses of buspirone, haloperidol and sulpiride were compared with diazepam in two experimental models of anxiety in rats. To achieve an optimal therapeutic response, at intervals of 2 to 3 days the dosage may be increased 5 mg per day, as needed. The maximum daily dose is 60 mg. Your healthcare provider will explain how to use buspirone effectively, including what time of day you should take your medication. At intervals of two to three days, the dosage can be increased an additional 5 mg as needed, until an ideal response is reached. The usual therapeutic dosage is 15 to 30 mg per day given in divided doses; the dosage should be individualized for each patient. General: The effectiveness of this drug for more than 3 to 4 weeks has not been demonstrated The recommended initial dose of Buspar is 7. Side effects generally only last a few days to a week or so, but you need sleep Additionally, both the 5 mg and 10 mg tablets are scored so they can easily be split in half, dropping the lowest available dose per tablet to 2. The recommended maximum daily dose is 60 mg.

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